Is It Working: Boneloss
Monitoring Clinical Markers
1. Bone Integrity & Pain
Fracture risk: No new fractures after minor bumps or falls.
Daily pain: Less constant bone or joint ache, especially in hips, spine, wrists.
Spinal changes: Slowing of stooping posture or vertebral compression.
Dental health: Less gum recession or tooth loss, since oral bone is an early marker of bone metabolism.
Stabilization is suggested if fractures don’t appear, or if pain lessens after 3–6 months.
2. Mobility & Strength
Balance: Fewer stumbles or near-falls when walking.
Endurance: Ability to walk, climb stairs, or carry groceries without faster fatigue.
Grip strength: Holding objects without slipping — a key frailty indicator.
Improvement in muscle–bone interaction may show within months via rhodiola, astragalus, and mushroom synergy.
3. Mineral & Hormonal Balance
Calcium metabolism: Stable serum calcium and phosphate (if monitored).
Vitamin D levels: Not declining, improved if supplemented in parallel.
Parathyroid hormone (PTH): Not excessively rising (a marker of bone resorption).
Electrolyte tone: Himalayan salt and dulse providing trace minerals (magnesium, iodine) to support bone matrix.
Lab monitoring over 6–12 months reveals whether the tincture is slowing metabolic bone turnover.
4. Mood & Nervous System
Depression/anxiety: Reduced low mood associated with bone loss and frailty (St. John’s wort, blue lotus).
Cognitive clarity: Lion’s mane and shiitake may support sharper focus alongside bone support.
Stress resilience: Rhodiola and astragalus preventing cortisol-driven bone breakdown.
Mood stabilization is often visible within 4–8 weeks and sustains long-term compliance.
5. Gut & Nutrient Absorption
Digestive function: Fewer issues absorbing nutrients (dulse and lemon aiding mineral uptake).
Weight stability: Avoiding excessive frailty weight loss.
Bowel rhythm: More regular elimination, less constipation linked to immobility.
Gut improvements may be noticed within weeks, helping long-term mineral absorption.
6. Quality of Life Indicators
Daily independence: Can still perform dressing, bathing, cooking without needing more support than before.
Activity recovery: Less soreness or fatigue after walking or light exercise.
Confidence: Less fear of falling, leading to better social engagement.
A slowed decline in independence is the most practical, visible marker of efficacy.
7. Trajectory Markers (Long View)
Bone density (DXA scans): Plateau instead of steady annual decline. Typical loss is 1–2% per year post-menopause; stabilization here is a major success.
No fragility fractures: Especially hip, spine, or wrist, within 12–24 months.
Hospitalization avoidance: No admissions for fracture-related surgery.
Frailty scale: Slowed progression on tools like the Clinical Frailty Scale (CFS).
If bone density stabilizes and fractures are avoided over 1–2 years, the tincture is effectively working.
Timeline expectations:
Weeks (2–8): Mood, digestion, stress resilience.
Months (3–6): Less daily bone pain, steadier mobility.
Year (6–12 months): Fewer fractures, slower posture changes.
Long view (12–24 months): Stabilized bone density scans, preserved independence.