Is It Working: Advanced Parkinson’s

Signals that tell you whether stabilization or leveling out is happening


1. Motor Symptoms

  • Tremor: Less frequent or less intense tremor during the day.

  • Rigidity: Decrease in “cogwheel” stiffness when stretching or moving.

  • Bradykinesia (slowness): Shorter time to initiate walking or standing up.

  • Falls / Freezing: No increase in frequency; fewer “sudden stops” when moving through doorways.

If motor symptoms hold steady over 3–6 months instead of worsening, that’s a sign of stabilization.

2. Non-Motor Symptoms

  • Sleep quality: Longer, deeper sleep; fewer awakenings from stiffness or vivid dreams.

  • Constipation: More regular bowel movements (a key gut–brain marker).

  • Mood / Anxiety: Less apathy, irritability, or anxiety spikes.

  • Fatigue: More endurance in daily activities without early exhaustion

 Improvements here can often be felt within weeks, and are early indicators that the tincture is shifting inflammatory and oxidative tone.

3. Cognitive & Emotional Function

  • Memory / word-finding: Not declining as fast; fewer moments of confusion.

  • Attention span: Able to follow conversations or tasks with less distraction.

  • Mood resilience: More “good days,” less sudden depression or emotional lability.

 If mood and cognition hold or improve slightly, that shows neuroprotective signaling (lotus, schisandra, quercetin) may be helping.

4. Medication Response

  • Levodopa window stability: If the time between doses where medication works (“on time”) doesn’t shrink.

  • Fewer fluctuations: Less dyskinesia or “off” episodes.

  • Absorption: If gut health improves, levodopa may last longer or feel more reliable.

 Stable medication response over months is a powerful marker of slowed progression.

5. Quality of Life Indicators

  • Independence: Can still dress, feed, or toilet without needing more help than 6 months ago.

  • Speech: Voice not weakening further; fewer “whispery” or slurred words.

  • Social engagement: Still attending family events, enjoying activities, less withdrawal.

 If daily life doesn’t decline, that is the clearest practical sign the tincture is working.

6. Trajectory Markers (long view)

  • No new complications (pneumonia, UTIs, bedsores) after 6–12 months.

  • Hospitalizations avoided due to stronger baseline resilience.

  • Plateaus in disease score: Tools like the UPDRS (Unified Parkinson’s Disease Rating Scale) or even a simple personal log of symptoms showing no worsening over months.

 How to judge success:

  • Weeks (2–6): watch digestion, sleep, mood.

  • Months (3–6): check whether motor decline has slowed.

  • Year+ (6–18 months): look for “plateaus” where disease severity hasn’t changed, when normally it would worsen.